Overnight sleep deprivation increases concentrations of B-amyloid peptide associated with dementia syndromes

Overnight sleep deprivation increases concentrations of B-amyloid peptide associated with dementia syndromes

Researchers assessed the effect of the sleep deprivation on the accumulation of B-amyloid peptide, which is highly associated with Alzheimer's disease. They found that in healthy individuals, the deprivation of the ground overnight significantly increases the concentration of the peptide in the thalamus and in the right hippocampus, compared to the control (the same individuals after a night of restful sleep).

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