National plan for Genomics

National plan for Genomics

The DNA of a living being is its genome. For a sustainable development, Chile needs a National Plan for Genomics as public policy. The Plan has 3 pillars: obtain the genome of Chileans to implement personalized medicine, genomes of productive species (economic sustainability) and biodiversity (conservation) genomes.

Genomics is a powerful tool for meeting the challenges of this century. Worldwide, Genomics is used today for personalized medicine, improve production and learn about nature. Chile risks a serious delay in their development. Despite a series of isolated efforts, we don't have a strategic vision to use the resources we have for - through Genomics - contributing to Chileans health, improve the competitiveness of our economy and preserving our biodiversity. (1) the ageing of our population will cause health care costs to increase. Current medicine has general protocols that are not optimal for all patients. The response of the developed countries to meet this challenge is personalized medicine, in which each person's DNA is used to optimize time, accuracy and costs of diagnosis and therapy. (2) competitive climate change threatened the domestic industry linked to the exploitation of natural resources (food, wood, fishing). Genomics allows to develop crops and products that adapt better to this phenomenon. (3) our biodiversity, rich heritage unique in the world, also is threatened by global change.

We propose the creation of a National Plan of genomics for the sustainable development of Chile within the framework of the Agenda by 2030, as a public, budget program, for: 1) defined in a participatory strategic guidelines for the development of the Genomics and social dissemination of this knowledge. (2) on the basis of the strategic guidelines, coordinate networking of scientists throughout Chile for: i. a reference of the Chilean to enable population genome the personalized medicine in Chile ii. The genome species affecting our development as a power food and exporting as well as native species. In this way, we prepare for coping with climate change, give it sustainability and diversify the productive sector and preserving our biodiversity. 3) to invest in physical, human and technological resources that allow us to take on this challenge. 4) propose a regulatory framework, particularly in relation to the storage and management of information, and an institutional framework that guarantees continuity and coordination of stakeholders. 5) encourage the application of the knowledge generated with the Plan in the areas of health, industry and environmental sciences.

Requirements for viability
Our scientific community is ready for this challenge. Initiative 1000 Genomes is composed of five scientific national centres of excellence and is supported by a network of researchers across the country. However, to promote a National Plan for Genomics, is key that the State involved to: 1) lead a participatory process that provides strategic guidelines for the development of genomics. 2) create institutions to set standards, and to promote a regulatory framework for the use of genomics. 3) invest resources for training of scientific talent, sequencing and a computing platform that can accommodate the immense volume of data that will be generated by the project. The support and leadership of the State of Chile are fundamental to the development of genomics in a way aligned with the common good, and to give the market new tools for innovation and development. In addition, there is a key political support that can be given to this initiative from the Congress. Finally, it is necessary to educate the public about the importance of genomics in health, economy and environment, all fundamental Chile achieve the objectives proposed for 2030, and thus contribute to the prioritization of the Plan within the public policy.

Importance for Chile
Genomics is a tool that contributes to the development of a society more equitable, productive and tuned with their environment. It is essential that promote a public policy on the subject, through a Plan coordinated from the public sector. (1) obtain a reference of the Chilean population genome allows the development of personalized medicine. This leads to more timely diagnoses, cost, and the development of therapies for the genetics of each patient. Thus, improves the quality of life for Chileans and reducing costs in the health system. (2) Genomics applied to the productive sector will allow to use natural resources in a sustainable manner and in harmony with the conservation of the environment. We are living a climate change with accelerated desertification and rising temperatures globally so it is crucial for a reinvention of the agriculture, livestock and aquaculture. Advance in this line will mean technological innovation, greater competitiveness, economic growth and welfare for our population. (3) Finally, our country is a place privileged by its diverse ecosystems, which have unexplored genetic reserves, whose preservation is crucial not only for the country but for the planetary future.