Prof. Mauricio Báez gets FONDEQUIP whose new equipment be located to the faculty at the global forefront on the study of biological macromolecules and their functioning in the cellular context

Prof. Mauricio Báez gets FONDEQUIP whose new equipment be located to the faculty at the global forefront on the study of biological macromolecules and their functioning in the cellular context

Prof. Maurio Báez

With five projects selected, out of a total of 28 nationally, the University of Chile again obtained for the second consecutive year, the maximum amount of funding in the FONDEQUIP Medium Scientific and Technological Equipment Competition. In its seventh version, the body awarded resources that will be aimed at implementing and updating infrastructure to strengthen research in biophysics, nano-manufacturing devices and advanced microscopy, among other areas.

The main axes of the FONDEQUIP Medium Scientific equipment and technology competition are to promote the scientific development of the country, promote intra- and inter-institutional cooperation, and encourage the sharing of new infrastructure or equipment .

Among the initiatives awarded is the initiative"Confocal fluorescence microscopy equipment coupled to optical tweezers for simultaneous manipulation and visualization of molecular systems", led by our academic, Mauricio Báez, an academic in the Department of Biochemistry and Molecular Biology.

With the funding obtained, the C-trap microscope will be installed, which uses light to observe very small systems, such as proteins and cells, along with manipulating them. This will provide unprecedented information on the functioning of molecular systems and machines, helping to enhance the area of studyin singleand associative research between different units of the University.

According to Professor Baez, "this new team will place the Faculty at the global forefront of the study of biological macromolecules and their functioning in the cellular context. These are of great relevance in many lines of research associated with the development of drugs and nanotechnology. On the other hand, it will allow academics to understand the functioning of their models, such as regulating RNA transcription, translocating proteins through pores or how chaperones work. In my case, it will be very useful to understand the mechanisms of protein formation and how molecular motors degrade them in the cell."

Through the combination of fluorescence microscopy techniques and optical tweezers, the device will be able to acquire force information, distance between optical traps and irradiation data simultaneously and correlatively. In this way, 12 researchers from the North Campus and the Faculty of Sciences of the University of Chile will benefit, generating new knowledge in biophysics, cellular and structural biology, among other areas.

The other winning projects belong to the Faculty of Sciences and Faculty of Physical Sciences and Mathematics.

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Source:www.quimica.uchile.cl