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Felix Rey is is a structural biologist who obtained his PhD in 1988 at Paris XI, and then went for a 7-years post-doctoral period at Harvard university, until 1995, where he specialized in the structure of viruses. He became a Junior PI in 1995, working at CNRS in Gif-sur-Yvette (Paris area), where in 1999 he became Director of the CNRS Laboratory of Structural and Molecular Virology. In 2004, he joined Institut Pasteur as Head of the Virology Department (which he directed until 2012), and in parallel he launched the Structural Virology Unit, which he still directs today.  His research focus has included the 3D structures of viral polymerases (like the hepatitis C virus RNA-dependent RNA polymerase) and the nucleoprotein template of replication for negative stranded RNA viruses such as the respiratory syncytial virus. But his main focus has been the study of viral envelope proteins, how they induce fusion, and how they are recognized by potently neutralizing antibodies. His studies in this area have very important implications in “reverse vaccinology”, open the way for epitope-focused vaccine design for viruses such as dengue and Zika. Felix Rey is an EMBO member since 2005 and a member of the French Academy of Sciences since 2010. Among the honors and awards he obtained are the CNRS “Médaille d’Argent” in 2004,  the Beijerink Virology Prize of the Dutch Royal Academy in 2013 and the Pasteur-Weizmann-Servier award in 2015.