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Dr. Daniel F. Hoft is a Professor and Director of the division of Infectious Diseases, Allergy & immunology in the department of Internal Medicine of Saint Louis university School of Medicine. He Started His Career in Science graduating in 1977 with a bachelor of Chemistry at Grinnell College, Iowa, He attended the university of Missouri, where he graduated in Medicine in 1985. He returned to Iowa to pursue a Ph.D. at the University of Iowa, where he graduated in the Immunology and Microbiology program in 1992, after many years dedicated to the University of Iowa Dr. Hoft was granted the Dianna and J. Joseph Adorjan Endowed Chair of Infectious diseases and Immunology. Dr. Hoft has led 14 NIH grants, as well 15 human vaccine trials with Bovine Calmette-Guerin and other types of vaccines. Among Dr. Hoft Work he has Developed Vaccines for Chagas Disease, Improved Tuberculosis vaccines and Pandemic Influenza Vaccine development. Dr. Horf current NIH-funded work focuses on investigations of the basic mechanisms of mucosal and systemic immunity protective against mucosally transmitted, chronic intracellular pathogens. Most of his research involves 3 human pathogens: Mycobacterium tuberculosis (Mtb), the protozoan parasite Trypanosoma cruzi and influenza. Dr. Hoft has published more than 80 publications in different highly respected Journals, including, Journal of Immunology, Cancer Research, Human vaccines & immunotherapeutics, Vaccine and PLoS Pathogens, among others.