Millions of patients worldwide suffer from heart failure, a chronic, deadly and costly syndrome. Research into its underlying molecular basis is necessary in order to understand the disease mechanisms, and thereby, design effective medical therapy to improve patient outcome.
Heart failure is often familial, suggesting a genetic cause. We are a basic science cardiology group working on experimental models of heart failure, with particular focus on genetic/inherited heart failure. We are based at IEMR, and have extensive national and international research collaboration. We combine a range of molecular biology techniques and analyses. In particular, we are interested in understanding the role of proteoglycans in the heart. Our experimental models and samples include heart biopsies from patients, mouse models with overexpression or knock-out of proteins, mouse models with human disease-causing mutations (e.g. familial HCM and DCM), heart tissue from mice and rats, and cultures of cardiac cells such as fibroblasts and cardiomyocytes.
The PhD fellowship is for three years. The PhD fellow will be employed on a Research Council of Norway (RCN) grant and will have the group leader, Dr. Ida Gjervold Lunde, as main supervisor. All PhD students at the Medical Faculty at UoO take part in the PhD program.
We are looking for talented and highly motivated candidates of all nationalities who have a strong interest in basic science and cardiac research. The applicant is expected to hold a MSc degree in natural and medical sciences, or an MD degree. The working language at IEMR is English, and the candidate is expected to be fluent in English. Previous experience in physiology, animal experiments, cell- and molecular biology research and techniques will be a significant advantage. Medical doctors with an interest in laboratory work and molecular biology are also encouraged to apply. Good communication and interpersonal skills, and ability to work independently are expected. The job requires some travelling.
Please apply through this webpage: