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Dr. Thomas G. Gillette received his PhD from New York University Sackler Institute, where he did his thesis work focusing on DNA replication. From that time on his research efforts have been primarily centered on the role of cellular responses to stress, either environmental, physical or metabolic. He moved from New York down to Dallas, Texas to University of Texas Southwestern Medical Center (UTSW) in 1998 and started his post-doctoral work with Errol Friedberg. His work uncovered a non-canonical role for the 26S proteasome in response to UV irradiation. In 2004 he was appointed as faculty in Physiology at UTSW, and continued his work on both canonical and non-canonical roles of the ubiquitin proteasome pathway (UPP) in cell stress responses. In 2009 he transferred to the department of Internal Medicine at UTSW and was promoted to Associate Professor in 2016. His recent research directions are on understanding the molecular mechanisms of heart disease, focused primarily on the cellular responses to cardiac stress.