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Figure 1: Antibacterial mechanisms of Silver Nanoparticles.

 

From this perspective, silver nanoparticles have also found diverse applications in wound dressings, coatings for medical devices, creams, impregnated textile fabrics, food storage containers, cosmetics, refrigerator surfaces, etc.

Besides applications, the antimicrobial activity is associated with high effectiveness, low toxicity and virtually no resistance of microorganisms to the presence of this metal.

The appearance of new bacterial strains resistant to antibiotics is a serious health problem, so there is a strong incentive to develop new bactericides. This makes current research in bactericidal silver nanomaterial particularly invaluable.

Most studies have determined that the antimicrobial activity of silver nanoparticles is governed by their size, shape, and capping agent, and by pH, ionic strength, and the presence of salts and organic molecules. But recent efforts have focused on their impact on human health and the environment due to their explosive use and current applications as a universal biocide.

References

[1] Manuel I.  Azócar, Laura Tamayo, Esteban Vargas, Nelson Vejar and Maritza Páez. Antimicrobial Activity: Antibacterial Properties of Silver Nanomaterials. CRC Concise Encyclopedia of Nanotechnology, Chapter: I, 2015.

[2] Manuel I Azócar, L. Tamayo, N. Vejar, G. Gómez, X. Zhou, G. Thompsom, E. Cerda, M. J Kogan, E. Salas, M. A Paez.  A systematic study of antibacterial silver nanoparticles: efficiency, enhanced permeability, and cytotoxic effects. Journal of Nanoparticle Research 16 (9), 1-9

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